Jordan Sorokin is an experienced neuroscientist and data scientist, with nearly 20 years of combined wet- and dry-lab research across a variety of domains, including 7 years of experience in high-throughput ML-enabled drug discovery. Throughout his career he has helped develop state-of-the-art machine learning models with an emphasis on translatability to scientific applications, built scalable and durable software, led drug and disease program teams, and guided cross-disciplinary scientific strategy.
He is motivated by the application of novel technologies to accelerate scientific research, providing mentorship and guidance to others, and collaborating across technical domains.
Publications
Effective Biological Representation Learning by Masking Gene Expression
K Kenyon-Dean, A Selega, I Bendidi, JM Sorokin, L Bertinetto, D Errington, H Donnella, O Kraus
ICLR 2026 Workshop FM4Science · 2026 · arXiv:2605.31562
Self-supervised transcriptomics model (TxFM) and a curated training corpus, DiverseRNA-1.4M, for gene-expression representation learning.
Neuroimmune cortical organoids overexpressing C4A exhibit multiple schizophrenia endophenotypes
MM Stanton, S Modan, PM Taylor, HN Hariani, JM Sorokin, BG Rash, et al.
bioRxiv · Jan 2023 · bioRxiv
Optimization and scaling of patient-derived brain organoids uncovers deep phenotypes of disease
K Shah, R Bedi, A Rogozhnikov, P Ramkumar, Z Tong, B Rash, M Stanton, JM Sorokin, et al.
bioRxiv · Aug 2020 · bioRxiv
Thalamic activity patterns unfolding over multiple time scales predict seizure onset in absence epilepsy
JM Sorokin, A Williams, S Ganguli, JR Huguenard
bioRxiv · Mar 2020 · bioRxiv
Identification of unique pre-epileptic states via non-negative tensor decomposition of single unit recordings
JM Sorokin, S Ganguli
Computational and Systems Neuroscience (COSYNE) · Feb 2019
Abstract and poster, COSYNE 2019.
Breathing control center neurons that promote arousal in mice
K Yackle, LA Schwarz, K Kam, JM Sorokin, JR Huguenard, JL Feldman, et al.
Science · Mar 2017 · Science
Regulation of thalamic and cortical network synchrony by Scn8a
CD Makinson, BS Tanaka, JM Sorokin, JC Wong, CA Christian, AL Goldin, et al.
Neuron · Mar 2017 · Neuron
Bidirectional control of generalized epilepsy networks via rapid real-time switching of firing mode
JM Sorokin, TJ Davidson, E Frechette, AM Abramian, K Deisseroth, JR Huguenard, JT Paz
Neuron · Jan 2017 · Neuron
Real-time optogenetic switching of thalamocortical firing modes to initiate and abort absence seizures in freely behaving rodents.
Absence seizure susceptibility correlates with pre-ictal β oscillations
JM Sorokin, JT Paz, JR Huguenard
Journal of Physiology–Paris · Nov 2016 · Journal
Brain-wide maps of synaptic input to cortical interneurons
NR Wall, M De La Parra, JM Sorokin, H Taniguchi, ZJ Huang, et al.
Journal of Neuroscience · Apr 2016 · J Neurosci
Adverse functional effects of chemotherapy on whole-brain metabolism: a PET/CT quantitative analysis of FDG metabolic pattern of the "chemo-brain"
JM Sorokin, B Saboury, JHA Ahn, M Moghbel, S Basu, A Alavi
Clinical Nuclear Medicine · Jan 2014 · Journal
Education
PhD, Neuroscience
Stanford University · 2019
Dissertation: Neural Dynamics Underlying Initiation and Control of Pathological Thalamocortical Oscillations
Neurosciences Graduate Training Program
Stanford University
Grants & fellowships
F31 Predoctoral Research Grant
NIH · NINDS · Sep 2016 · Stanford University School of Medicine
Supported three years of doctoral research. Identified pre-seizure neural activity predicting absence seizure onset and differential roles of the cortex and thalamus in seizure initiation.
Experience
Researcher
Amae Health · Jun 2026–present
Staff Data Scientist, Computational Biology
Recursion · Jun 2023–Jun 2026
Senior Scientist, Computational Biology
Recursion · Feb 2022–Jun 2023
Senior Machine Learning Scientist
Herophilus · Nov 2020–Feb 2022 · San Francisco, CA
Machine learning across biological domains; disease program lead; experimental design with software engineers and biologists.
Computational Neuroscientist
Herophilus · Aug 2019–Nov 2020 · San Francisco Bay Area
Hierarchical mixed-effects generalized additive models in Python; parallelized image processing on AWS Batch; program co-lead.
Neuroscience PhD Candidate
Stanford University School of Medicine · Sep 2013–Aug 2019
Huguenard Lab, Neurology — mechanisms of absence epilepsy using electrophysiology, optogenetics, and applied mathematics. Probed thalamocortical roles in seizure initiation, maintenance, and termination.
Instructor, Computational Techniques for the Biosciences
Stanford University · Sep 2016–Jan 2019 · part-time
Co-instructed a data science course for the biosciences (calcium imaging, sequence alignment, EEG/time-series decomposition); taught every fall for three years.
Independent Researcher
University of Pennsylvania Health System · Jan 2011–Jul 2013 · Philadelphia, PA
Adverse effects of chemotherapy on regional and whole-brain glucose metabolism via PET/CT; first-author publication in Clinical Nuclear Medicine.
Research Assistant
Salk Institute for Biological Studies · May 2012–Nov 2012 · La Jolla, CA
Thalamo-cortical inhibitory interneuron networks in mouse barrel and visual cortex; publication in Journal of Neuroscience.
Independent Researcher
Center for Positive Psychology, University of Pennsylvania · Jan 2011–Sep 2011
Economic fluctuations and affect, depression, and life satisfaction; forecasting effects of economic crises.
Summer Intern
Salk Institute · Jun 2007–Aug 2007
Slesinger Lab — HEK cell culture/transfection; TIRF and epifluorescence imaging of PSD95 in drug metabolism.
Software & code
Open-source tools for neuroscience and data analysis — scalable software, clustering, time-series analysis, and neural simulation utilities.
- HDBSCAN — Hierarchical density-based clustering (MATLAB)
- SingularSpectrum — Singular-spectrum analysis for time series (MATLAB)
- ModelNeuro — Hodgkin–Huxley neuron simulation (Python)
- neo-matlab — MATLAB interface for extracellular electrophysiology datasets
Service
Arts and Culture Board, City of Fort Collins — member, term through March 2028. Advises on arts programming, public art, and cultural services.
Languages
English
Native or bilingual proficiency
Spanish
Professional working proficiency